Año 1972
Autores Beales DL , Burry HC , Grahame R - Más
Revista British medical journal
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In a double-blind between-patient study of aspirin and benorylate carried out in 72 outpatients with rheumatoid arthritis, benorylate 4 g twice daily was shown to be an effective analgesic and anti-inflammatory drug, its effects being indistinguishable from those of aspirin 1.2 g four times daily. Compared with the pretreatment values both drugs produced a statistically significant improvement (P < 0.01) in functional grade, overall pain, articular index, and grip strength at the end of the first and second weeks. The overall incidence of side effects was less with benorylate, though this difference was not significant at the 5% level.

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Año 1975
Autores Coigley MH - Más
Revista The Practitioner
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Año 1973
Autores Hingorani, K. - Más
Revista Rheumatology
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A Double blind study of benorylate and ibuprofen was carried out in 27 patients with classical rheumatoid disease. Both drugs were shown to have effective analgesic and anti-inflammatory properties. Although patient preference was for benorylate, fewer complained of side effects with ibuprofen.

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Año 1974
Autores Malcolm, Alastair - Más
Revista Journal of International Medical Research
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Benorylate was compared with indomethacin in a double-blind cross-over trial in patients with rheumatoid arthritis. Twelve patients completed treatment. All measurements showed a trend towards benorylate giving greater improvement, although the differences were not statistically significant. Nine patients out of the twelve preferred benorylate.

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Año 1973
Autores Sperryn PN , Hamilton EB , Parsons V - Más
Revista Annals of the rheumatic diseases
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