Paget's disese - updated focus emphasizing the development of a correct dignosis

Objective: The Paget's disease, a disorder of focal bone remodeling is characterized by an excessive absorption followed by intense neoformation of the affected bone, presenting an important genetic component wifh evidence of heterogeneity. Usually found occasionally, typical of adulthood and variable treatment, the disease is able to affect several bones, simultaneously, causing deep deformities, requiring, therefore, further studies in order to clarify the diagnosis, since the symptoms are not always clear Therefore, this study aimed to update the etiology and clinical aspects of the disease, in order to provide data that subsidize the choice of methods for the establishment of a correct diagnosis. Method: There was research on the World Wide Web and the online data bases Medline and LILACS, coverillg journi published from 2000 to 2008, of which were selected for review the ones of most importance arigorous about this disease. Books published in the same period were also consulted. Conclusions: The diagnosis, generally, is based on clinical, radiographic, biochemical, genetic and histological aspects and the methods of image are easier to obtain, with emphasis on conventional radiography because low cost and its specificity, and the whole body scintigraphy as a method of choice for tracking suspicious lesions, due to its high sensitivity.