Novel 12-membered ring macrolides with activity against erythromycin-resistant organisms.

Aún no traducido Aún no traducido
Autores
Categoría Estudio primario
RevistaThe Journal of antibiotics
Año 2003
A series of novel 12-membered ring macrolides was designed based on available information on structure-activity relationships and macrolide-ribosome interactions. Compounds with the desosamine and the anchor group properly attached to the 12-membered lactone ring exhibited improved activity against erythromycin-resistant organisms.
Epistemonikos ID: 74c6403ce9b1fa09b404cc5f066e35ae38fdb32b
First added on: Sep 16, 2024