Triglyceride- glucose index as simple marker associated with atherosclerotic cardiovascular disease in a tertiary care hospital in Pakistan

Identification of patients at early risk for CVD improves risk stratification and patient management. Triglyceride glucose index can be used as a marker of atherosclerotic cardiovascular disease. This study was approved by IRB of the institute and conducted in the period of July 2020 to June 2022 in the Chemical Pathology laboratory of Indus Hospital. All patients whose cardiac intervention (PCI/LHC) performed were included. Fasting lipid profile was analyzed on Alinity C analyzer, and FBS was measured on glucometer. TyG index was calculated, 54% have TyG index more than 9.04. Male predominance was observed, with 68.6% falling within the <9.04 range and 60.4% within the >9.04 range. Patients aged over 50, constituting 51 (59.3%) in the <9.04 TG index group and 60 (59.4%) in the >9.04 TG index group. Patients with TyG index <9.04, majority FBS is in pre-diabetic range 45.3% while TyG index >9.04 group, majority FBS is in diabetic range with a p-value of <0.001. Our study demonstrated that the TyG index was independently associated with atherosclerosis in our population and this marker can be used for the prediction of disease for healthy individuals.