Comparative efficacy of exosurf and survanta surfactants on early clinical course of respiratory distress syndrome and complications of prematurity.

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类别 Primary study
期刊Journal of perinatology : official journal of the California Perinatal Association
Year 1998
連結 Pubmed
目的：确定新生儿及Survanta表面活性剂对Exosurf病程早期急性呼吸窘迫综合征（RDS），动脉血气，呼吸支持，结果发病率及并发症的早产儿RDS的疗效比较。 研究设计：203早产儿的新生儿呼吸窘迫综合征机械通气，谁收到了4个救援的Exosurf或Survanta的剂量，从医疗记录进行回顾性分析。 结果：各组分别为出生体重和胎龄相媲美。虽然这两个随机组小部分吸入氧浓度（FIO2）和通气支持，一个显着更大的改善，证明FIO2呼吸功能的基础上，RDS的严重程度是相似的，平均气道压，分压肺泡 - 动脉氧分压差，和氧指数，观察到在Survanta组（P <0.05）由12小时至48小时（对<0.01）。结果发病率比较胎龄表现出较高的早产儿视网膜病变的发生（P <0.02）之间的较大婴儿（28至32周）谁是与Exosurf处理。 结论：，Survanta RDS的早期临床过程中产​​生了显着更快的响应速度相比，Exosurf。然而，最后的呼吸结果无差异的影响进行了观察。因此，我们得出这样的结论：这两种表面活性剂是有效的，用于治疗的RDS。
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Epistemonikos ID: df2da1e4650d9d8dee88735c41048d75e7da2eb2
First added on: Feb 02, 2013
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