Improvement of muscle strength in familial hypokalaemic periodic paralysis with acetazolamide.

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作者
类别 Primary study
期刊Journal of neurology, neurosurgery, and psychiatry
Year 1988
8个家族hypokalaemic周期性麻痹患者的双盲交叉研究,以评估乙酰唑胺对肌肉力量的影响。所有患者均有减少发作的肌纤维传导速度。5例患者没有受到攻击的时间的研究。其中一名病人的研究,因为不良反应退出。11肌肉群的肌力与一个手持测力计测量。在7例患者(平均增加17%,P小于0.05,95%可信区间7.2-26.8%)显着改善力的总和。耐力测试结果表明,30个完整kneebends的性能改善。表面肌电图的测量结果显示在治疗过程中没有改变,肌纤维传导速度或功率谱。集成的肌电图呈(非有效)平均增长了21%。
Epistemonikos ID: 9cc421da74a6b8235b64cfe4e7bc9f72b94fce94
First added on: Oct 16, 2012
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