Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: results of the PROVED trial. PROVED Investigative Group.

Machine translation Machine translation
类别 Primary study
期刊Journal of the American College of Cardiology
Year 1993
連結 Pubmed, DOI
目标：本研究的目的是要确定是否有效的患者地高辛是慢性的，稳定的轻度至中度心力衰竭。背景：地高辛一直是传统的治疗心脏衰竭，但在早期的研究方法学方面的限制阻碍其疗效确切的结论。方法：退地高辛（安慰剂组，n = 46）或延续（地高辛组，n = 42）进行了前瞻性，随机，双盲，安慰剂对照多中心试验的患者与慢性，轻度至中度稳定继发性心力衰竭左室收缩功能不全谁是正常窦性心律，并接受利尿药和地高辛与长期治疗。结果：地高辛治疗的患者从最大运动撤回表明恶化的病人相比，谁继续接受地高辛（在锻炼时间的变化4.5 s）（p值= 0.003）的能力（在行使时-96中值的变化）。地高辛治疗的患者则有撤回治疗失败的发生率增加（p值= 0.039）（39％，地高辛戒断组主场迎战19％，地高辛维修组）和一下降至治疗失败时间（p值= 0.037）。此外，患者谁继续接受地高辛有一个较低的体重（P = 0.044）和心率（p值= 0.003）和更高的左心室射血分数（p = 0.016）。结论：这些数据提供了强有力的正常窦性节律和地高辛患者的临床疗效证据，轻，中度慢性心衰继发的收缩功能障碍谁与利尿剂治疗。
This translation has been produced by an automated software. If you wish to submit your own translation, please send it to translations@epistemonikos.org
Epistemonikos ID: 92d8f16bc1cba60261d764a48c5b892a659f2fe6
First added on: Jun 08, 2011
Warning
This is a machine translation from an article in Epistemonikos.

Machine translations cannot be considered reliable in order to make health decisions.

See an official translation in the following languages: English

If you prefer to see the machine translation we assume you accept our terms of use