Influence of antihypertensive drug treatment on morbidity and mortality in patients over the age of 60 years. European Working Party on High blood pressure in the Elderly (EWPHE) results: sub-group analysis on entry stratification.

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类别 Primary study
期刊Journal of hypertension. Supplement : official journal of the International Society of Hypertension
Year 1987
連結 Pubmed
：欧洲工作小组高老年（EWPHE）试验血压超过60岁以下的双盲随机安慰剂对照试验的抗高血压治疗的患者。入学标准既包括对安慰剂治疗坐在舒张压在90-119毫米汞柱范围和在160-239毫米汞柱收缩压范围。八百和40例病人随机分为要么积极治疗（氢氯噻嗪+氨苯喋啶）或安慰剂。如果血压持续升高甲基多巴，增加了活动方案和配套安慰剂给安慰剂治疗方案。随机分组之前，病人在八个阶层分层根据性别，年龄60至69岁或70岁以上，以及是否存在高血压或心血管并发症的情况下。无论是意向性治疗和对随机治疗，分析表明，从男性和女性积极治疗受益。取得了正式的统计意义，男性心血管疾病的死亡率（意向性治疗分析）和女性心血管事件。虽然事件发生率与以前的心血管事件和超过70岁组病患更大，减少心血管事件的百分比是在这些团体相似，无并发症，在60至69岁的患者。然而，从治疗可以证明没有什么好处的患者超过80岁。吸烟的存在或缺乏对这些反应在治疗老年无影响。
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Epistemonikos ID: 8379f2cc1bb182e9dfe127b4e9e7731e6ed1e0f4
First added on: Jun 08, 2011
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