Ciclopirox 8% nail lacquer topical solution for the treatment of onychomycosis in patients with diabetes: a multicenter, open-label study.

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类别 Primary study
期刊Journal of the American Podiatric Medical Association
Year 2007
連結 Pubmed
背景：一个开放标记，非比较研究以评估在患者的安全和环吡8％趾甲漆外用溶液效力与2型糖尿病。 方法：将40九糖尿病患者的远端甲下甲真菌病每日治疗一次，48周，环吡酮8％指甲油，批准用于患者的治疗轻度至中度甲癣外用钉子的解决方案。 结果：治疗导致临床改善的患者63.4％。大多数患者（85.7％）有改善或治愈真菌学结果，有54.3％达到真菌学治愈。考虑真菌学和临床疗效的患者84.4％的产生的改善，成功或治愈的治疗结果。此外，患者经历改善的钉（63.4％），指甲表面（56.1％），指甲颜色（48.8％），和指甲厚度（65.9％）的患病区域。环吡8％趾甲漆是安全的，具有有限的感染在一个病人，从而解决了15天的治疗相关的不良事件;患者完成了研究。没有与治疗相关的严重不良事件进行观察。 结论：环吡酮8％趾甲漆是一种安全，有效的治疗远端甲下甲癣患者2型糖尿病接受胰岛素或口服降糖治疗。
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Epistemonikos ID: 800e9fad6f1b4a1737de78ffd4da54cb43754985
First added on: May 23, 2014
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