Therapeutic Hypothermia Using Gel Packs for Term Neonates with Hypoxic Ischaemic Encephalopathy in Resource-limited Settings: a Randomized Controlled Trial

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作者 Bharadwaj SK, Bhat BV -More
类别 Primary study
期刊JOURNAL OF TROPICAL PEDIATRICS
Year 2012
連結 Pubmed, DOI
目的：探讨低温治疗（TH），使用凝胶包在降低死亡率和发病率在足月新生儿缺氧缺血性脑病的疗效，研究与TH的相关问题。 方法：缺氧缺血性脑病婴儿被随机分为TH和对照组。在TH组婴儿被冷却出生用布盖冷却凝胶包，以保持33-34℃。目标肛温前72h婴儿随访至6个月，使用巴罗达发育筛查测验进行了评估。 结果：有在基线参数无显著差异。TH组有显著降低死亡或发育迟缓的结合率在6个月以下的21％（在TH组8.1％比对照29％，RR 0.28，95％CI：0.11-0.70，P = 0.003）。 结论：TH用凝胶包减少死亡或发育迟缓在6个月以下的婴儿缺氧缺血性脑病的风险。
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Epistemonikos ID: 6598ca57c640ac545f52e06e4383ea1fe0d5c6bd
First added on: May 19, 2013
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