Once-daily, 3-day azithromycin versus a three-times-daily, 10-day course of co-amoxiclav in the treatment of adults with lower respiratory tract infections: results of a randomized, double-blind comparative study.

Machine translation Machine translation
作者 Gris P -More
类别 Primary study
期刊The Journal of antimicrobial chemotherapy
Year 1996
連結 Pubmed, DOI
为期3天的疗程的阿奇霉素（500毫克，每天一次）和合作amoxiclav（625毫克三每天三次）10天疗程相比，在67例患者的双盲研究急性传染病，慢性支气管炎急性发作（AIECBs ，N = 54），急性支气管炎（N = 7），或肺炎组（n = 6）。阿奇霉素，满意的临床反应（治愈或改善）与AIECBs，急性支气管炎和肺炎的1/2（100％）2/4（50％）24/28（86％）患者治疗的患者。反应令人满意，分别在24/26（92％），4/4（100％）和4/4（100％）患者，接受合作amoxiclav。肺炎链球菌和流感嗜血杆菌是最常见的病原菌在基线。在治疗结束后，基线病原体被消灭在9/10微生物课税与阿奇霉素治疗的患者，在治疗与合作amoxiclav 10/10。相关或可能与治疗相关的不良事件发生在每个治疗组5例;大部分这些事件的影响肠胃系统。在各治疗组的患者因不良事件停止治疗。因此，这项研究表明，注射一次，连续3天每天500毫克阿奇霉素是有效和耐受性良好，作为共同amoxiclav 10天，每日三次在家居治疗急性下呼吸道感染的成年人。
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Epistemonikos ID: 479d92dd4446c25f837659655b1fbafe28ff6c19
First added on: Sep 05, 2011
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