A comparative study of calcipotriol ointment and tar in chronic plaque psoriasis.

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作者
类别 Primary study
期刊The British journal of dermatology
Year 1994
卡泊三醇软膏的抗银屑病的疗效,耐受性和安全性与焦油的前瞻性,左/右随机,研究者盲法对照研究进行了比较。卡泊三醇软膏50微克/克,每日两次施加到二分之一的身体。在相反侧,白色软石蜡在早晨施用,和煤焦油溶液BP 15%V / W在晚上含水膏。30例慢性稳定斑块型银屑病被招募。评估分别在2,4和6周进行。三例患者退出研究。在PASI评分的下降是在2,4和6周可见两侧。从基线两种治疗之间的差异都赞成卡泊三醇的统计学显著。改善与卡泊三醇是迅速的在第2周的治疗。用tar,发生显著改善仅经过4周的治疗。两个处理间出现红斑,硬结和脱屑从基线分数的差异均有统计学显著有利于钙泊三醇在所有评估点。七名患者制定了关于卡泊三醇治疗侧的刺激,但也有对焦油治疗侧无不良影响。在两名患者,与银屑病相关瘙痒是减少了钙泊三醇。虽然6周治疗后平均血清钙,磷水平保持在正常范围内,有与基线相比,其价值显著变化。
Epistemonikos ID: 425e5b5b92c29c3bc498f441e1b323161e7bf3e9
First added on: Apr 30, 2013
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