Multicenter comparison of azithromycin and amoxicillin/clavulanate in the treatment of patients with acute exacerbations of chronic obstructive pulmonary disease

Machine translation Machine translation
作者 Whitlock, W -More
类别 Primary study
期刊Current Therapeutic Research Clinical and Experimental
Year 1995
連結 DOI
这项随机，多中心，研究者盲，平行组研究比较了5天，每日一次当然阿奇霉素（第1天，2个250毫克的胶囊，接着是一个250毫克胶囊对天2至5）用10日，三次每日当然阿莫西林/克拉维酸（一个500毫克片剂）在70例慢性阻塞性肺疾病急性细菌性加重（慢性阻塞性肺病，慢性支气管炎）。在治疗结束时，所有29（100％）的功效课税与阿奇霉素治疗的患者被治愈或好转，给予27阿莫西林/克拉维酸（P = NS）计税患者25（93％）相比。细菌学根除率分别为86％（2529株），阿奇霉素和87％（2023株）与对照药。阿奇霉素的耐受性良好;考虑相关的或可能与治疗不良事件的报告中阿齐霉素的收件人的28％，与阿莫西林/克拉维收件人39％（P = NS）的比较。阿奇霉素的5天，每日一次治疗方案比得上在COPD患者的急性细菌恶化的治疗标准试剂。
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Epistemonikos ID: 3f38d613126e28d24893e453e4b4c967580502cd
First added on: Mar 23, 2015
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