Increased population prevalence of reflux and obesity in the United Kingdom compared with Sweden: a potential explanation for the difference in incidence of esophageal adenocarcinoma.

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类别 Primary study
期刊European journal of gastroenterology & hepatology
Year 2011
連結 Pubmed, DOI
目的：食管腺癌的发病率是在英国比在瑞典的5倍。我们研究建立风险因素的流行率在两个人群食管腺癌。 方法：比较胃食管反流症状，肥胖和烟草的英文随机抽样和年龄在40-59岁的瑞典人口之间的吸烟患病率以人口为基础的横断面研究。数据是通过自我报告的问卷收集。多因素Logistic回归分析得到的胜算比与95％置信区间，调整为潜在的混杂。 结果：样品由3633英语号和第1483瑞典人（应答率43和62％，分别）的。反流症状发生至少每周一次的患病率为两倍，共同在英国与瑞典样品比较。肥胖（BMI≥30）也几乎英语样本中两倍多见。吸烟的频率是在这两个国家的类似。的反流症状和至少25的BMI的组合是在英语三倍共同比瑞典样品中。 结论：反流症状和肥胖在英语人口样本的相当高的发病率与瑞典人口可能有助于食管腺癌，在英国的已知高发生率进行比较。
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Epistemonikos ID: 36f918505696262d1c4805945a1714038a74aad3
First added on: May 19, 2014
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