Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term

Machine translation Machine translation
类别 Systematic review
期刊Cochrane Database of Systematic Reviews
Year 2014
背景:Micafungin是棘白菌素。它抑制β-1,3-D-葡聚糖合成,从而达到几乎所有念珠菌属(包括对氟康唑耐药的那些)以及针对曲霉属的抑菌活性以及几种但不是全部致病性霉菌的杀真菌活性。来自体外研究,动物模型,小型临床试验的结果,暗示可能的未来适应症如侵袭性曲霉病和经验性viantifungal治疗,尽管目前很少有信息公布。目的:描述micafungin作为侵入性霉菌感染治疗的已发表数据,特别分析其在麻醉主机和重症监护环境中的作用。方法:采用主要医学检索引擎对文献进行系统评价。术语如米卡芬净,曲霉病,接合菌,侵袭性真菌感染,新出现的真菌感染,抗真菌治疗或治疗,抗真菌预防,经验性或预防性治疗。排除了发烧性中性粒细胞减少症患者。结果:确定了这些设置中的几项研究,并在本综述中进行了描述。虽然没有发表盲法随机临床试验,但是分析了开放性临床研究中描述的治疗或预防微创曲霉菌和其他侵袭性霉菌感染的方法。结论Micafungin可以作为一种或多种治疗或预​​防由霉菌引起的侵袭性真菌感染的单一或组合的主要或救援治疗发挥重要作用。需要进行新的随机临床试验来确认其疗效。
Epistemonikos ID: 250c0eddd23dc988a5548189feaa02af7bb01783
First added on: Jun 21, 2014
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