Effect of artificial tears and recombinant bovine basic fibroblast growth factor eyedrops on dry eye after glaucoma filtering surgery

AIM: To discuss the clinical effects of artificial tears and recombinant bovine basic fibroblast growth factor (rb-bFGF) eyedrops on dry eye after glaucoma filtering surgery. METHODS: All 60 cases(60 eyes) with dry eye symptom after glaucoma filtering surgery were chosen and randomly divided into two groups, treatment group and control group. In treatment group, the patients were treated by artificial tears and rb-bFGF eyedrops. In control group, the patients were treated by artificial tears. The subjective dry eye symptoms, fluorescein staining (FL), the time of tear secretion (Schirmer I test, S I t) and tear break-up time (BUT) were observed by slit lamp before treatment, 2 weeks and 4 weeks after treatment. RESULTS: There was no statistical difference between the two groups before treatment (P > 0.05). After treatment, the subjective dry eye symptoms, FL,S 11 and BUT were significantly different (P < 0.01). CONCLUSION: Artificial tears combined with rb-bFGF eyedrops can be effective to relieve the dry eye symptoms after glaucoma filtering surgery.