The changes and clinical significance of routine blood test in infants with rotavirus enteritis

Objective To investigate the changes and clinical significance of routine blood test in infants with rotavirus enteritis.Methods The white blood cell count (WBC),the platelet parameters (PLT),the platelet volume (MPV)and the platelet distribution width (PDW)were detected by automatic blood cell analyzer respectively in 314 infants with rotavirus enteritis before and after the therapy for 5 -7 days.The C -reactive protein (CRP)was also detected,then made comparison with the normal control group (40 cases).Results The WBC (10.77 ±4.20)× 109 /L,PLT(330.02 ±117.70)×109 /L,MPV(8.46 ±2.15)fL in the infants with rotavirus enteritis were higher than the WBC(7.69 ±2.06)×109 /L,PLT(298.45 ±57.19)×109 /L and MPV(7.52 ±0.85)fL in the control group before the therapy.The differences were statistically significant (t value =4.569,1.670,2.746,P =0.000, 0.000 and 0.047).The WBC(7.76 ±2.83)×109 /L and CRP(5.18 ±5.82)mg/L in the infants with rotavirus enteritis after the therapy were lower than the WBC(10.77 ±4.20)×109 /L and CRP(7.70 ±11.28)mg/L before the therapy(t value =9.794 and 2.810,P =0.000).Conclusion The WBC,PLT and CRP in infants with rotavirus enteritis were usually higher.But the raise of WBC and CRP could not be the only indication of using antibiotic in infants suffered from diarrhea.