Enhanced training on how to use a dry powder inhaler (DPI) improves the inhalation manoeuvre (IM) of patients with asthma (child 6-17 yrs and adult >17 yrs) or COPD and in healthy adults (HA) when they use a Spiromax® (S) and Turbuhaler® (T) DPI

Objective: A DPI should be used with an IM that is as deep and as fast as possible from the start of inhalation (Laube BL et al Eur Respir J 2011;37:1308-1331). We have determined the effect of enhanced training using the In-Check Dial (IC) while subjects inhaled through a S and a T DPI. Method: Child (CA: 6-17y) and adult (AA:18-45y) patients with asthma (mean FEV1 57 and 69% pred), COPD (52 % pred) and HA were randomised in an open-label design to receive IC with a S and a T. Two separate inhalations were measured using an inhalation profile recorder. The profile with the highest peak inhalation flow (PIF, L/min) was used for data analysis. Results: Figures 1 and 2 show the % improvement in the maximum pressure change (MPC, kPa) and the acceleration of the flow (ACC, kPa/sec) inside each DPI during an inhalation after IC. Conclusion: Enhanced training on DPI use may be an important factor in achieving greater drug delivery to the airways. Funding: Teva Pharmaceuticals.