A prospective randomised clinical study on evaluation of platelet-rich fibrin versus zinc oxide eugenol in the management of alveolar osteitis

Abstract Purpose The aim of this study was to evaluate the efficacy of platelet-rich fibrin (PRF) in the management of alveolar osteitis and further compare the results with those of zinc-oxide Eugenol (ZOE). Materials and methods A total of 40 patients with alveolar osteitis following extraction of mandibular molars were randomly divided into two groups on the basis of treatment, in which Group A patient's received PRF and Group B received ZOE as an obtundant dressing. Pain (VAS), degree of inflammation and number of exposed socket walls were noted and evaluated at 1st, 3rd, 5th and 7th post-operative day. Results Group A showed better and faster socket healing than Group B. However, symptomatic pain relief was faster in Group B than in Group A. Conclusion PRF might be a treatment of choice in the management of alveolar osteitis.