Sedative effects of maprotiline and amitriptyline.

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Auteurs
Catégorie Primary study
JournalActa psychiatrica Scandinavica
Year 1988
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By means of critical flicker fusion measurements and subjective estimation of drowsiness, experiments with 12 healthy subjects over periods of 8 h showed that maprotiline caused less than half the amount of sedation compared to amitriptyline, both drugs given in single doses of 50 mg. The experiments were blind, randomized and placebo controlled. Implications for clinical use are discussed.
Epistemonikos ID: 38746518f9998faab59dbd9f85e58446e0efd300
First added on: May 14, 2022