Effect of consumption of different legumes on blood glucose

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2019
INTERVENTION: The study will be a randomized, cross‐over dietary intervention on 25 participants. Each subject will require coming for 4 visits control, and 3 different processing (canned, pureed, and pasta) of chickpeas over a period of 2 weeks, the order of which will be randomized using a computer to assess the post‐prandial and 24h glycaemic effect by using continuous glucose monitors. The food will be prepared in the food tech lab at the University of Leeds according to the procedure followed by the food lab to avoid any risk of contamination. Before a test day, participants will be asked to fast overnight, to refrain from strenuous exercise for 24 hours and to refrain from drinking alcohol during the evening before the study visit. Their blood glucose will be measured on arrival the following morning by taking blood via a finger prick test then small device for continuous glucose monitoring will be attached to their upper arm by qualified practitioner (it will remain inserted there until they finish all four visits within two weeks, instructions about it will be provided) and a blood sample will be taken. Then they will be asked to consume either pureed chickpeas, canned chickpeas or chickpeas made pasta or potatoes only provided by the researcher. They will also be asked to abstain from all foods (can drink water) during the following 3 hours. Two more blood samples will be taken at 90 min and 180 min after eating. The procedure will be conducted on weekdays only with test food given alternatively at each session. They will be asked to answer some questionnaires related to food intake. CONDITION: Healthy volunteers ; Digestive System PRIMARY OUTCOME: Blood glucose will be measured on arrival the following morning by taking blood via a finger prick test then small device for continuous glucose monitoring will be attached to their upper arm by qualified practitioner. Two more blood sample will be taken at 90 min and 180 min after eating. SECONDARY OUTCOME: ; 1. Insulin and satiety hormones measured using the same blood samples collected as above.; 2. Inflammatory markers measured using the same blood samples collected as above.; 3. Food habits measured by the food frequency questionnaire during each visit.; INCLUSION CRITERIA: 1. Aged >= 18 years 2. Healthy 3. BMI 18 ‐ 30
Epistemonikos ID: ff6275490ca2b717b00cc81b48f1d50693493a3f
First added on: Aug 24, 2024