Green tea extract in the treatment of candidiasis

INTERVENTION: Administration (nistatin)4 times a day, every time (15_20 drops) mouthwash for 5min Intervention 1: Administration (nistatin)4 times a day, every time (15_20 drops) mouthwash for 5min. Intervention 2: The patients will be recommended to use mouthwash 4 times a day each time 15‐20 drops for 5 min and after that they should prevent from eating and drinking for 30 minutes, and they are suggested to use the drug in two weeks at a specific time. The patients will be recommended to use mouthwash 4 times a day each time 15‐20 drops for 5 min and after that they should prevent from eating and drinking for 30 minutes, and they are suggested to use the drug in two weeks at a specific time. Treatment ‐ Drugs CONDITION: Chronic Erythematosus Candidiasis. ; Oral thrush Oral thrush PRIMARY OUTCOME: Inflammation of the mucosal surface of the denture. Timepoint: On days 0, 7, 14. Method of measurement: By the investigator using graded abslang. The number of candida colonies. Timepoint: On days 0, 7, 14. Method of measurement: By culture on Sabouraud's dextrose agar plates. INCLUSION CRITERIA: INCLUSION CRITERIA: Those with lesions clinically associated denture stomatitis in the active phase can be reached to confirm an oral specialist (Diagnostic criteria are the swelling and inflammation below the denture surface). Exclusion criteria: Those who cannot continue to the end of study because of the social or personal reasons; patients with Diabetes mellitus, immune deficiency such as acquired immune deficiency syndrome (AIDS), as well as those who will benefit antibacterial drug therapy, corticosteroids, radiotherapy and smokers will be excluded.