The effects of combined Mediterranean, gluten-free, lactose-free and low-FODMAP diets accompanied with supplemental formula, and with the consumption of turmeric in patients with ulcerative colitis

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2023
INTERVENTION: Intervention 1: Intervention group: After calculating the amount of calories needed by each person using the Meflin formula, a diet with 75% of the calories needed to maintain weight is set based on the principles of the Mediterranean diet, gluten‐free, lactose‐free, low FODMAP and turmeric consumption. The remaining 25% is provided by standard formulas for 6 weeks. Intervention 2: Control group: After calculating the amount of calories needed by each person, using the Mefflin formula, the usual food plan is adjusted according to the calories needed to maintain weight for 6 weeks. CONDITION: K51.9 ulcerative colitis. ; Ulcerative colitis, unspecified PRIMARY OUTCOME: Disease Activity Index. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire. Life Quality. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire. Serum hs‐CRP. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa. TAC. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa. TNF‐a. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa. SECONDARY OUTCOME: BMI. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Calculation. Weight. Timepoint: At the first of research and end of research( 6th week). Method of measurement: scale. INCLUSION CRITERIA: Samples with inflammatory bowel disease confirmed by histopathology The duration of the disease is less than two years The disease is active in a mild to moderate stage (diagnosis of the severity of the disease is the responsibility of the treating physician) Not consuming alcohol and drugs Not suffering from other diseases and intestinal disorders, known autoimmune diseases, cancer, inflammatory and infectious diseases Not using multivitamin‐mineral, omega‐3, polyphenolic and antioxidant supplements, probiotics as well as the non‐use of anticoagulants such as heparin and warfarin, NSAIDs such as ibuprofen, aspirin and diclofenac, antihistamines and calcium channel antagonists such as nifedipine in the past month BMI over 18.5 and under 30 Age 18 years and above No change in the type and dosage of the drug consumed during the past mont
Epistemonikos ID: feaee483a9f5f9d3af5bc28c52729e4c46daf0c5
First added on: Feb 20, 2024