Effect of Intravenous Lignocaine Versus Fentanyl on Quality of Recovery QoR 15 in Patients Undergoing Septoplasty or Functional Endoscopic Sinus Surgery Under General Anaesthesia

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: inj lignocaine infusion: Inj. lignocaine (1.5 mg/kg bolus diluted to 10 ml 0.9% normal saline followed b y a 1.5 mg/kg/h infusion till the end of surgery Control Intervention1: inj fentanyl infusion: inj fentanyl (2ug/ kg bolus diluted t o 10 ml 0.9% normal saline followed b y an infusion of 0.5 ug/kg/h till the end of the surgery Control Intervention2: inj. normal saline: no drug will be administered. inj normal saline will be given in control group. CONDITION: Health Condition 1: O‐ Medical and Surgical PRIMARY OUTCOME: comparison of the quality of recovery QoR following administration of intravenous lignocaine versus fentanyl versus normal saline in patients ; undergoing septoplasty or FESS surgeries under general anaesthesiaTimepoint: pre OP ; ; 5 mins ; ; after 24 hours SECONDARY OUTCOME: Secondary outcomes will be the time and no. dosage required of rescue analgesia, severity of post operative ; pain and any other adverse effect noted. ; Timepoint: Post op ; immediately after shifting ; 1 hr ; 4 hr ; 6 hr ; 12 hr ; 24 hr INCLUSION CRITERIA: 1.Patients willing to sign informed consent 2.Male or Female patients between 18 to 65 years of age 3.Patients belonging t o American Society of Anaesthesiologists physical status I & II 4.Patients posted for septoplasty OR FESS under general anaesthesia.
Epistemonikos ID: fe5df84f49cf93705fb177f5339bfe30c44481eb
First added on: Oct 08, 2026