Does a single oral dose of dexamethasone after successful emergency department treatment of migraine reduce the incidence or severity of rebound headache within 48 hours?

Category Primary study
Registry of TrialsANZCTR
Year 2005
INTERVENTION: The primary aim is to compare the proportion of patients who experience rebound headache within 48 hours after ED treatment of migraine between a group treated with single dose oral dexamethasone 8mg and a group treated with placebo.Secondary aims are to compare headache severity, analgesia/ health service use, adverse events and return to normal functioning between the groups. CONDITION: Migraine PRIMARY OUTCOME: Proportion of patients who were discharged pain free that have a recurrence of headache within 48 hours Proportion of patients who were not pain free at discharge whose headache is worse or unchanged within 48 hours SECONDARY OUTCOME: Adverse events and return to normal functioning between the groups. Analgesia/ health service use Comparison of headache severity. INCLUSION CRITERIA: Consenting adult patients with physician‐diagnosed migraine treated in the ED who are willing and able to be contacted between 48‐72 hours after discharge for follow‐up.
Epistemonikos ID: fd4ffe584230f5e9fcc85f6994682587a0ec789d
First added on: Aug 25, 2024