The ADDITION Study. Intensive Treatment in People With Screen Detected Diabetes in Primary Care. - Full Text View - ClinicalTrials.gov

The ADDITION study comprise 2 parts: screening for Type 2 diabetes and intensive treatment compared to standard treatment. In the screening study, the feasibility and results of country specific models to identify undiagnosed individuals with Type 2 diabetes will be evaluated. In the treatment study the effects of routine care in general practice according to local and national guidelines will be compared with an intensive ADDITION protocol, including structured lifestyle education (dietary modification, increased physical activity and smoking cessation) and intensive treatment of blood glucose, blood pressure and lipids, and prophylactic aspirin with or without motivational interviewing, on mortality, macrovascular and microvascular disease. Furthermore the impact of treatment on health status, treatment satisfaction and health service costs will also be assessed.