The Effect of Central Insulin on Insulin Sensitivity and Energy Metabolism

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2011
Insulin has a direct effect on the energy metabolism of the brain under basal conditions and has an effect on the hepatic glucose production, lipid metabolism and the secretion of various hormone. The effect of intranasal insulin on peripheral metabolism in humans supposedly is mediated by the vagus nerve. The purpose of this study is to determine whether central insulin influences the human peripheral insulin sensitivity of liver and muscle and whether vagus nerve stimulation can mimick this effect.
Epistemonikos ID: fc1bf136fbc4823d344636085e18d956228ef9e0
First added on: May 10, 2024