Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2018
Based on a priori analysis the investigators will need 100 subjects in a placebo arm (normal saline) and 100 subjects in a treatment arm (3% sodium chloride), for a total of 200 patients. This study will be conducted on healthy subjects with normal renal function undergoing anterior cervical discectomy and fusion for degenerative indications only. Subjects will be randomized to the treatment or placebo arm (which will be double blinded). Subjects in the treatment arm will begin to receive intravenous 3% sodium chloride before the incision is made. The solution will be given at a rate of 10 cc/hour over a period of 24 hours. Baseline, post‐operative, and delayed post‐operative dysphagia surveys will be administered either in person or by telephone. The investigators hope to decrease the incidence and severity of post‐operative dysphagia.
Epistemonikos ID: fc1b8968726571cc0d4ec6094a68d423faac2973
First added on: May 21, 2024