Clinical Study of Acupuncture Combined with Moxibustion in the treatment of Chemotherapy induced Peripheral Neuropathy

INTERVENTION: Acupuncture point selection: Hegu (LI4), Taichong (LR3), Quchi (PC3), Neiguan (PC6), Zusanli (ST36), Xuehai (SP10), Fenglong (ST40), Yanglingquan (GB34), Shixuan (EX‐UE11), Sanyinjiao (SP6), Taixi (KI3). All acupoints were selected according to the positioning standards in the National Standards of the People's Republic of China, Meridian Points Locations [29], and the treatment was completed by professional acupuncturists with more than 5 years of acupuncture and moxibustion experience, and the treatment lasted for 4 weeks.Moxibustion was continued after the end of acupuncture. Moxibustion acupoint selection: Guan Yuan (RN4), Qi Hai (RN6), Zusanli (ST36). Experimental Other acupuncture combined with moxibustion CONDITION: Acupuncture; Moxibustion; Chemotherapy; Peripheral neuropathy Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy, which has a serious impact on the quality of life of patients. At present, there is no targeted and reliable treatment plan. To investigate the efficacy and safety of acupuncture combined with moxibustion in the treatment of CIPN, a randomized controlled trial was conducted. ; Acupuncture; Moxibustion; Chemotherapy; Peripheral neuropathy PRIMARY OUTCOME: TNS , including 11 scoring items. 4 weeks evaluate the symptoms and signs of peripheral neuropathy, motor and sensory neurophysiology examination, touch, vibration perception, quality of life, etc. SECONDARY OUTCOME: evaluate the symptoms and signs of peripheral neuropathy, motor and sensory neurophysiology examination, touch, vibration perception, quality of life, etc. 4 weeks ranging from grade 0 to grade 4 INCLUSION CRITERIA: (1) Have received chemotherapy (complete at least one complete cycle), the primary disease condition is stable; (2) Symptoms of chemotherapy‐induced peripheral neuropathy after the end of chemotherapy; (3) Age not less than18 years and not more than80 years; (4) Karnofsky's performance status (KPS) score was greater than 60; (5) Predicted survival time not less than 6 months; (6) The patient has signed informed consent.