To see which medicine helps babies breathe better after surgery.

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Sugammadex: Reversal of neuromuscular blockade using intravenous sugammade X‐ 2mg/Kg at the end of surgery. Control Intervention1: Neostigmine: Reversal of neuromuscular blockade using intravenous neostigmine‐ 50mcg/Kg and intravenous glycopyrrolate‐ 10mcg/Kg at the end of surgery. CONDITION: Health Condition 1: O‐ Medical and Surgical PRIMARY OUTCOME: Diaphragmatic excursion ratioTimepoint: ; 5 minutes after extubation ; SECONDARY OUTCOME: Atelectasis scoreTimepoint: 5 minutes after extubation Diaphragm thickness at end‐expiration, diaphragm thickness at end‐inspiration, diaphragm thickening fractionTimepoint: 5 minutes before induction, ; 5 minutes after extubation, ; 30 minutes after extubation ; Diaphragmatic excursion ratio.Timepoint: 30 mins after PACU admission Peri‐operative respiratory adverse events including laryngospasm, bronchospasm, ; oxygen desaturation, excessive coughing and postoperative stridor, post‐operative painTimepoint: 1 hour after the end of surgery INCLUSION CRITERIA: ASA‐PS I and II, children aged 2 months to 2 years undergoing elective surgeries under general anaesthesia
Epistemonikos ID: fbd054a4c53043897d07ac87e400e1eb2f269f1d
First added on: Oct 08, 2026