Vagus nerve stimulation treatment for erythematotelangiectatic rosacea: a multi-center, randomized clinical trial

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Transcutaneous auricular vagus nerve stimulation group:Transcutaneous auricular vagus nerve stimulation;sham stimulation group:sham stimulation; CONDITION: Erythematotelangiectatic rosacea (ETR) PRIMARY OUTCOME: Clinician’s Erythema Assessment score; SECONDARY OUTCOME: Patient Health Questionnaire–9;Global Flushing Severity Scale;Generalized Anxiety Disorder–7;Facial Itch Numerical Rating Scale;Patient Self‐ Assessment score; INCLUSION CRITERIA: 1. Subjects aged between 18 and 60 years (inclusive, with no gender restrictions); 2. Meeting the diagnostic criteria for erythematous telangiectatic rosacea and having a CEA score of 2 or higher; 3. Capable of adhering to the study or follow ‐ up procedures, and collaborating in observing adverse events and therapeutic effects; 4. The patient's voluntary participation in the study and signing of a written informed consent form.
Epistemonikos ID: fae86369bf902db54e0eaf3ffdac364b3aabeacc
First added on: Mar 07, 2026