Complement activation after aortic endothelial injury.

Authors
Category Primary study
JournalSeminars in thrombosis and hemostasis
Year 1986
Ischemic endothelial cell injury results in C activation that precedes partially via the classic pathway. This may be relevant to clinical situations of ischemia such as occur during embolization or thrombus formation. The generation of C activation products (such as C3a and C5a) may mediate many of the inflammatory changes observed in infarcted tissues.
Epistemonikos ID: f9eb5d308d70ae789a2dfa3cdf39e4d015dcefb6
First added on: May 24, 2023