Effect of sugammadex and neostigmine on intraocular pressure

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2014
INTERVENTION: Sugammadex is the intervention of the study. This drug is the first selective relaxant binding agent. In the study, sugammadex was given as an intravenous injection and each patient received only a single dose . The dosage of Sugammadex is 4mg/kg. Sugammadex was administered at the completion of surgery. CONDITION: Intraocular pressure changes were investigated after the general anesthesia in patients who scheduled for arthroscopic surgery in supine position. The patients have American Society of Anaesthesiologists physical status (ASA) 1‐2. PRIMARY OUTCOME: Evaluation of intraocular pressure changes with sugammadex and ; neostigmin + atropin with a Tono‐Pen XL applanation tonometer. SECONDARY OUTCOME: To investigate the effects of sugammadex and neostigmine on complications (gagging, nausea, vomiting, breath holding, laryngospasm, and tremors) after extubation. To investigate the effects of sugammadex and neostigmine on hemodynamic parameters (heart rate, mean arterial pressure, peripheral arterial oxygen saturation). Heart rate, mean arterial pressure and peripheral arterial oxygen saturation were measured by electrocardiography, non‐invasive oscillometric metod and pulse oximetry. INCLUSION CRITERIA: Patients aged 18–65 years with ASA I–II risk status who underwent arthroscopic surgery under general anesthesia
Epistemonikos ID: f9aee62623f3ea2d3538eec0c820712e2971edb1
First added on: Aug 25, 2024