Intra Articular Ankle Fractures

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2022
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human ankle. We hypothesize that early intervention with percutaneous joint lavage in the first 0-48 hours after injury will attenuate the production of pro-inflammatory cytokines, MMP\'s and cartilage breakdown products compared to non-lavaged control subjects at the time of surgical fixation.
Epistemonikos ID: f9a6e2b503f801adfbe694cd975c4a04292addce
First added on: May 13, 2024