Suun limakalvolle annosteltu fentanyyli luuydinaspiraatioon ja -biopsiaan liittyvän kivun hoidossa

INTERVENTION: Trade Name: Abstral Pharmaceutical Form: Dispersible tablet INN or Proposed INN: FENTANYL CITRATE CAS Number: 990‐73‐8 Pharmaceutical form of the placebo: Dispersible tablet Route of administration of the placebo: Transmucosal use (Noncurrent) CONDITION: This study is performed on adult patients with suspected or known hematologic disease undergoing bone marrow aspiration and biopsy. Study investigates oral transmucosal fentanyl in the treatment of pain associated with bone marrow aspiration and biopsy. PRIMARY OUTCOME: Main Objective: Comparing transmucosal fentanyl with placebo in the treatment of pain associated with bone marrow aspiration and biopsy. Primary end point(s): Pain defined as NRS (numeral rating scale, 0‐10) during different phases of the bone marrow aspiration and biopsy procedure Secondary Objective: INCLUSION CRITERIA: ‐ adult patients with known or suspected hematological disease undergoing bone marrow aspiration and biopsy Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18‐64 years) F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) F.1.3.1 Number of subjects for this age range