Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial

As an investigator initiated and conducted, multicentre, ambulance‐delivered, prospective, randomised, open‐label, blinded outcome (PROBE) study. INTERACT4 aims to evaluate the effects of functional outcome according to an ordinal analysis of the full range of scores on the mRS, the safety in all randomised patients; reperfusion treatment (thrombolysis and/or thrombectomy) related symptomatic ICH (sICH, according to standard definitions), infarct size, the time to and overall rate of reperfusion treatment in AIS patients; hematoma volume and early expansion in ICH.