Evaluation of two dental materials in regenerative treatment of non-vital teeth with incomplete root development

INTERVENTION: Twenty non‐vital immature permanent anterior teeth with apical periodontitis were included in this study. Samples were randomly distributed at www.randomizer.org into two groups (n=10) based on the used coronal plug materials; group I (GI): Well Root PT (Vericom, Gangwon‐Do, Korea), and group II (GII): MTA Biorep (Itena Clinical, Paris, France). Treatment was conducted according to the American Association of Endodontics guidelines (18/05/2021). All patients in both groups were treated with the same protocol except for the application of coronal plug material. The sodium hypochlorite (1.5 %) was used for irrigation and the triple antibiotic paste (5 mg/mL) was used as a medication. The scaffold used was a blood clot. Follow‐up was done clinically and radiographically for up to 12 months for the two groups. CONDITION: Treatment of necrotic immature teeth with apical periodontitis ; Oral Health PRIMARY OUTCOME: The degree of success is measured using the American Association of Endodontists' criterion at baseline and 12 months SECONDARY OUTCOME: The following secondary outcome measures were assessed at baseline and 12 months:; 1. Pain on biting is measured by asking the patient if it is present or absent; 2. Pain on percussion is measured by tapping the tooth with a mirror; 3. Soft tissue swelling is measured using visual examination; 4. Sinus tract is measured using visual examination; 5. Mobility is measured by applying pressure with two metal instruments; 6. Pulp sensitivity is measured using Ethyl Chloride spray; 7. Root length is measured radiographically using Image J software; 8. Root thickness is measured radiographically using Image J software; 9. The area of the periapical lesion is measured radiographically using Image J software INCLUSION CRITERIA: 1. Patients are free from any systemic diseases that may hinder the normal healing process 2. Non‐vital permanent anterior teeth with open ape Xand apical periodontitis 3. Single‐rooted teeth 4. The tooth does not require post and core for the final restoration 5. Age range from 9‐25 years old