Fish oil supplementation in pregnancy to reduce allergies in early childhood

INTERVENTION: 3 x 500mg high‐DHA rich tuna oil capsules per day taken from 18‐21 weeks gestation until birth CONDITION: Allergic Disease PRIMARY OUTCOME: Medical diagnosis (from a clinical examination) of allergic disease (eczema, asthma, allergic rhinitis or food allergy) with sensitisation (determined by a positive skin prick test to food allergens or aeroallergens) in the child SECONDARY OUTCOME: Any Sensitisation (determined by a positive skin prick test to food allergens or aeroallergens) in the child Medical diagnosis (from a clinical examination) of allergic disease (eczema, asthma, allergic rhinitis or food allergy) without sensitisation in the child INCLUSION CRITERIA: Child to have a family history of medically diagnosed allergic disease (eczema, asthma, allergic rhinitis): singleton pregnancy less than 18‐21 weeks gestation with no known fetal abnormality: mothers not to have had documented history of alcohol or drug abuse: no participation in other clinical trials with fatty acid intervention.