Meta Analysis of Needling and Western Medicine for Perimenopausal Depression Symptoms

Objective To compare the clinical efficacy of needling and Western medicine in the treatment of perimenopausal depression by using evidence-based medical methods. Method of retrieving clinical research literature on acerbic treatment of perimenopausal depression in PubMed, Cochrane, Embase, Web of Science, Chinese Journal Database, Chinese Biomedical Biomedical Library .by 2 majors Literary readers used ENDNOTE X8 to manage the literature based on the inclusion of standard screening literature, evaluated the quality of the literature using the Cochrane Evaluation Manual, and used Reman5.3 for statistical analysis. The results were included in 31 randomized controlled trials with a total of 2638 patients.Meta analysis results showed: in total efficiency [OR=2.29,95,% CI ( 1.83 to 2.87), P<0.00001] and MENQOL (standardized average standard deviation (SMD) = -0.45,95% CI (-0.72~-0.17), P=0.001] were statistically significant, acupuncture group efficacy was significantly better than the western medicine group. 1.34~ 0.17), P=0.13], serum estradiol (E2) [SMD=-0.07,95% CI (-1.30~1.15), P=0.91), follicular genesis hormone (FSL) (SMD=-0.41,95% CI (-1.05~0.22), P=0.20), luteopoietin (LH) (SMD=0.06,95% CI (-0.17 to 0.28), P=0.61] The difference is not statistically significant, the acupuncture group is comparable to the Western drug group. Conclusion acupuncture improves menopausal depressive symptoms, quality of menopausal life clinical efficacy is better than western medicine, improves menopausal syndrome symptoms, regulatory hormone levels are comparable with western medicine.