A Study Comparing Berberine containing Mouthwash, Chlorhexidine Mouthwash, and Salt water in patients with gum disease

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Berberine containing mouthwash: Patients will be advised to rinse for at least 1 min with 10 mL of berberine mouthwash twice daily in the interval of 12 h for 14 days and will be advised to avoid rinsing and food consumption for half an hour. Control Intervention1: 0.2% chlorhexidine mouthwash: Patients will be advised to rinse for at least 1 min with 10 mL of 0.2% chlorhexidine mouthwash twice daily in the interval of 12 h for 14 days and will be advised to avoid rinsing and food consumption for half an hour. Control Intervention2: Saline mouthwash: Patients will be advised to rinse for at least 1 min with 10 mL of saline mouthwash twice daily in the interval of 12 h for 14 days and will be advised to avoid rinsing and food consumption for half an hour. CONDITION: Health Condition 1: K051‐ Chronic gingivitis PRIMARY OUTCOME: The Berberine containing mouthwash has a ; significant anti‐microbial and anti‐plaque effect ; on the clinical signs in dental plaque‐induced ; gingivitis patientsTimepoint: baseline (0 day) with follow up after 7 days and ; 14 days for evaluation SECONDARY OUTCOME: NILTimepoint: NIL INCLUSION CRITERIA: 1.Patients with periodontal pocket depth less than 3mm and no clinical attachment loss. 2.Patients willing for participation and have provided written consent.
Epistemonikos ID: f7d52da1c933fb463accfc943cce34e83507c566
First added on: Jul 21, 2026