Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation

The two most common consequences resulting from aspiration are chemical pneumonitis and bacterial aspiration pneumonia. Both entities present with comparable clinical signs and symptoms. In the absence of a reliable clinical or biological marker to differentiate between these two conditions, most patients with suspected aspiration are treated empirically with antibiotics. De‐escalation of initial antibiotic treatment is encouraged based on the results of microbiological results, usually performed before starting antimicrobial treatment. However, in most hospitals, 48‐72h are required to obtain the results of microbiological cultures, and to de‐escalate empirical large spectrum antibiotic treatment. The use of the Unyvero®, a multiplex PCR‐based testing system, for detection of respiratory bacterial pathogens would allow decreasing the percentage of patients with aspiration syndrome who will receive unappropriated antibiotic treatment at Day 3.