Amplitude Titration to Improve ECT Clinical Outcomes

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2023
A randomized controlled trial will compare hippocampal neuroplasticity, antidepressant, and cognitive outcomes between individualized amplitude and fixed 800 mA amplitude ECT in older depressed subjects (n = 25 per group, n = 50 total). Relative to fixed 800 mA ECT: H1: Individualized amplitude arm will have improved RUL antidepressant outcome (IDS-C30 response rates and reduced BT electrode placement switch at V2). H2: Individualized amplitude arm will have improved cognitive outcomes (DKEFS-Verbal Fluency
Epistemonikos ID: f6815e9190940d5a8876ce29af5688b6fe0cfd7b
First added on: Feb 19, 2024