Glue Embolization Without Surgical Resection for Orbital Venolymphatic Malformation.

A 59-year-old man presented with worsening left-sided eye pain and headache from a left orbital venous-dominant venolymphatic malformation. He reported a history of sclerotherapy, experiencing only transient relief with this procedure. Oral analgesia had not helped alleviate the pain. He described the pain as dull and intermittent, and noted worsening with physical exertion. Physical examination revealed dense left optic neuropathy, motility restriction, enophthalmos, and Valsalva-induced proptosis. Given baseline enophthalmos and poor vision affecting the left eye, glue embolization without surgical resection was offered. He underwent 2 rounds of percutaneous n-Butyl cyanoacrylate embolization performed 11 months apart. Following these procedures, he reported sustained pain relief, as compared with prior sclerotherapy procedures. Glue embolization without surgical resection may provide a novel approach to orbital venolymphatic malformations in selected patients.