Effect of curcumin-piperine in patients with coronavirus(COVID-19)

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Intervention group: Two curcumin‐piperine capsules (500 mg of curcumin + 5 mg of piperine) will be given daily for 2 weeks after lunch and dinner. Intervention 2: Control group: 2 placebos (500 mg of maltodextrin) daily after lunch and dinner for 2 weeks. CONDITION: coronavirus (covid‐19) disease. ; COVID‐19 Disease U07.02 PRIMARY OUTCOME: Albumin. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: blood sample. ALT. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Enzymatic photometric method. AST. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Enzymatic photometric method. Blood oxidative stress indices ( SOD, MDA, TAC). Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: By using available commercial kits. Body temperature. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: By using clinical thermometer. BUN. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: urine sample. CBC. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: blood sample. Creatinine. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: by laboratory kit. CT of the chest. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Find out ‐ Photos ‐ CT. Duration of hospitalization. Timepoint: At the time of discharge from the hospital. Method of measurement: By Using the patient's medical record. ESR. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Enzymatic method. Hs‐CRP. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Enzymatic method. LDH. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Enzymatic photometric method. Severity and number of coughs. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Visual analogue scales (VAS) for cough. Severity of the disease. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: By using clinical and laboratory evaluations. INCLUSION CRITERIA: Tendency to participate in the study People aged 18‐65 years Diagnosis of Covid‐19 based on clinical findings and imaging findings (Chest X Ray), CT scan or PCR
Epistemonikos ID: f46f47c2dabb163bf5fe03560d04e7a0ec250f5b
First added on: May 04, 2020