Efficacy of 15% cholestyramin ointment on pain reduction after hemorrhoidectomy

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: 15% Cholestyramin ointment with almond oil on the site of rectal wound, immediatly after surgery and 12 hours later then 3 gr three times daily for 14 dayes Almond oil, on the site of rectal wound immediatly after surgery and 12 hours later then 3 gr three times daily for 14 dayes Intervention 1: 15% Cholestyramin ointment with almond oil on the site of rectal wound, immediatly after surgery and 12 hours later then 3 gr three times daily for 14 dayes. Intervention 2: Almond oil, on the site of rectal wound immediatly after surgery and 12 hours later then 3 gr three times daily for 14 dayes. Treatment ‐ Drugs CONDITION: heamorrhoid grade III, IV. ; Internal haemorrhoids with other complications Internal haemorrhoids with other complications PRIMARY OUTCOME: Doses of opioid or Tramadol. Timepoint: 48 hours after surgery. Method of measurement: Sum of injected doses. Pain after defecation. Timepoint: 12, 24, 48 hours and 2, and 4 weeks after surgery. Method of measurement: VAS. Pain after surgery. Timepoint: 12, 24, 48 hours and 2, and 4 weeks after surgery. Method of measurement: VAS. INCLUSION CRITERIA: INCLUSION CRITERIA: Age between 20 and 70 years, presence of hemorrhoid grade III or IV Exclusion criteria: Presence of anal fissure, previous hemorrhoidectomy, substance abuse, pregnancy, presence of cirrhosis, and receiving oral Nitroglycerin or Cholestyramine
Epistemonikos ID: f354745e15ae8d1bb658a593fb7084f9e76adf8a
First added on: Apr 22, 2021