Dietary fat, airway inflammation and bronchodilator response in asthma - Study 1

INTERVENTION: At each visit, participants will consume a study meal. The order in which the study meals will be consumed will be randomly allocated. There will be a washout period of 1 week between visits. The study meals are as follows: 1. Fat: 100mL double cream, providing 45g (96%) fat, 29g saturated fat, 1740kJ. 2. Carbohydrate: 104g high energy drink, providing 100% carbohydrate, 1740kJ. 3. Control: 100mL water Participants will be asked to consume each meal within a 15 minute timeframe. On arrival baseline lung function will be performed followed by the administration of a short acting B2‐agonist (salbutamol 400ug, inhaled via a spacer). The participant will then consume the study meal. Participants who complete Study 1 may also participate in Study 2. CONDITION: Asthma PRIMARY OUTCOME: Lung function (FEV1, FVC) assessed using spirometry. SECONDARY OUTCOME: Respiratory impedance using impulse oscillometry. INCLUSION CRITERIA: Stable asthma, non smokers