Activity of platelets in patients recovering from severe infection

Authors
Category Primary study
Registry of TrialsNetherlands Trial Register
Year 2017
INTERVENTION: Aspirin intake for 10 days Group 1: no aspirin intake Group 2: 80mg aspirin intake in the evening Group 3: 40mg aspirin intake twice‐daily CONDITION: Pneumonia, Platelet reactivity, Aspirin, Urinary tract infections, Cutaneous infection ; ; PRIMARY OUTCOME: Platelet aggregability, measured by:; ; ‐ PFA‐200 parameters (closure time, flow slope, maximum rate of occlusion, area under the curve); ; ‐ TBX2 serum levels SECONDARY OUTCOME: ‐ Laboratory endpoints: platelet‐, reticulared platelet‐, leucocyte count, CRP, BSE, haemoglobin level ; ; ‐ Cardiovascular events INCLUSION CRITERIA: ‐ Primary diagnosis of pneumonia ‐ 50 years or older on the date of hospital presentation ‐ Hospitalization for at least 24 hours, receiving at least 1 dose of antibiotics within 48 hours of admission
Epistemonikos ID: f2a5271f501ce9a3058a46726a19ba0c165cbc7d
First added on: Aug 23, 2024