Vagus nerve stimulation for epilepsy: Randomized comparison of three stimulation paradigms

Authors
Category Primary study
JournalNEUROLOGY
Year 2005
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/( on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.
Epistemonikos ID: f1d8577a703aee2ffa635d313baa9a93ec571e7e
First added on: Apr 14, 2015