modifications on the pain-threshold in labour and the effects of the epidural analgesia and S-Ketamina on the pai-threshold

INTERVENTION: Trade Name: ketanest Pharmaceutical Form: Solution for injection INN or Proposed INN: Ketamine Concentration unit: mg milligram(s) Concentration type: equal Concentration number: .375‐ Pharmaceutical form of the placebo: Solution for injection Route of administration of the placebo: Intravenous use CONDITION: pain‐threshold ; MedDRA version: 6.1 Level: HLT Classification code 10029772 PRIMARY OUTCOME: Main Objective: estimate modifications on the pain‐threshold in labour and the effects of the epidural analgesia and S‐Ketamina on the pai‐threshold Primary end point(s): nd Secondary Objective: to estimate maternal‐fetal effect; to estimate the effectiveness on the extension of analgesic action of epidural opioids INCLUSION CRITERIA: primiparae age 18‐40 ASA I‐II no maternal‐fetal disease Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18‐64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range