Pregnancy and breast cancer

The objective of this work is to determine the incidence, clinical and the pathological behavior and the treatment of patients with diagnostic of breast cancer and pregnancy. We retrospectively reviewed 7 patients with histories of breast cancer associated with pregnancy, treated at the Institute of Oncology “Dr. Miguel Perez Carreño” from theyear 2001 to the year 2010. The mean age was 32 years (42%). The gestational age corresponded to 3 patients 8, 18 and 29 weeks respectively, 3 postpartum and 6 weeks in the postoperative mediate mastectomy. Only one ingested oral contraceptives for 3 years. The predominant histological type was infiltrating ductal carcinoma 5 (71.4%) patients followed by invasive lobular carcinoma and the apocrine type. The tumor size ranged from 3 cm to 5 cm, only 1 (14.2%) patients consulted with a lesion of 1 cm size, stage IIIA disease occurred in 3 (42.8%) patients, one patient stage IV, stage I: One patient, stage IIA: 1 patient. 5 (71.4%) patients received neo-adjuvant chemotherapy which completed treatment with total mastectomy more axillaries dissection of levels I-II of Berg, only one was a conservative surgery and palliative treatment. Regarding the case was a triple immunohistochemistry negative. The management of the breast cancer during pregnancy should be made according to the stage and consider the emotional aspect involved in this decision